Pertussis

Pertussis, or whooping cough, is an acute infectious disease caused by the bacterium Bordetella pertussis. Pertussis is primarily a toxin-mediated disease. The bacteria attach to the cilia of the respiratory epithelial cells, produce toxins that paralyze the cilia, and cause infelammation of the respiratory tract, which interferes with the clearing of pulmonary secretions. Pertussis antigens […]

Typhoid Fever

Typhoid fever is a life-threatening illness caused by the bacterium Salmonella Typhi.  In the United States about 400 cases occur each year, and 75% of these are acquired while traveling internationally.  Typhoid fever is still common in the developing world, where it affects about 21.5 million persons each year. Typhoid fever can be prevented and […]